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Maternal Age: Region

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* Download Region Anomaly Group data as Excel spreadsheet - contact SWCAR to get access to this dataset  [Help]

Figures reflect cases (babies/children) with one or more anomalies in that group or sub-group, born to a mother who falls into that age range, expressed as a percentage of all cases of that anomaly group or sub-group notified to us. Cases with multiple anomalies within the same anomaly group or sub-group, are counted only once in that group or sub-group. For example, a baby with transposition of the great vessels and a VSD will be counted once in each of the ‘transposition great vessels’ and ‘VSD’ minor sub-groups, once in each of the ‘All complex cyanotic CHD’ and ‘All septal defects’ sub-groups, but only once in the ‘Circulatory’ group.

The maternal age is taken as being that at the end of the pregnancy.

Anomaly grouping < 20 20 - 24 25 - 29 30 - 34 35 - 39 40 - 44 > 44 Age Not Known
  % % % % % % % %
A: Neurological 8.0 19.8 23.7 25.9 17.1 4.3 0.3 0.9
All neural tube defects 17.9 26.9 26.3 16.3 3.4 0.3 0.6  
anencephalus 26.3 24.8 15.6 3.8 0.4     7.3
spina bifida 28.5 27.2 17.3 3.1 0.3 0.9   8.4
encephalocele 22.7 26.7 16.0 2.7   1.3   12.0
Congenital hydrocephalus 19.0 23.3 27.1 18.2 4.6 0.3 1.1  
Muscular dystrophy   33.3 50.0 16.7        
Duchenne MD 40.0 40.0 20.0          
B: Eye Ear Face Neck 5.3 18.3 22.7 26.6 19.8 6.3 0.3 0.6
All eye 19.8 21.0 28.1 18.8 4.2   0.7  
anophthalmos / microphthalmos 15.0 23.3 23.3 5.0   1.7   6.7
congenital cataract 22.2 25.6 17.8 4.4   1.1   7.8
anomalies surrounding structures 21.3 36.3 16.3 3.8       6.3
All ear 17.1 22.6 29.5 19.2 4.8 0.7 0.7  
external ear anomalies 23.4 23.4 25.5 4.3       4.3
sensorineural hearing loss 15.8 31.6 21.1 5.3       7.9
C: Circulatory 7.2 16.8 24.4 26.8 17.9 5.8 0.5 0.8
Disordered circulation 19.4 18.3 27.7 19.9 5.8 1.0    
All septal defects 15.4 24.3 28.5 17.7 5.9 0.5 0.8  
ASD (all types) 24.2 27.4 18.2 7.1 0.9 0.2   7.8
VSD 24.8 29.4 16.8 5.2 0.2 1.0   6.8
AVSD 18.5 24.9 22.1 10.0 2.4     8.0
All complex cyanotic CHD 15.4 27.2 27.8 16.9 4.4   0.6  
transposition great vessels 30.2 30.2 15.6 2.6   1.0   7.3
tetralogy of Fallot 23.3 24.7 18.5 6.8       8.2
All heart valve anomalies 16.7 23.8 27.5 16.8 6.1 0.7 0.4  
pulmonary valve anomalies 21.8 27.1 15.8 7.3 0.9 0.6   8.5
tricuspid valve anomalies 28.7 21.7 19.6 7.7       7.0
mitral valve anomalies 25.0 35.7 11.9 6.0 1.2 1.2   6.0
aortic valve anomalies 22.7 32.8 15.7 4.8 0.9     7.9
All vessel anomalies 17.5 23.6 26.9 18.4 5.2 0.2 0.6  
pulmonary artery anomalies 22.5 24.9 18.5 6.0       9.6
aorta anomalies 21.7 29.6 19.0 4.8 0.5 0.7   8.6
All chamber anomalies 18.3 25.4 27.5 15.2 4.5 0.5 0.3  
hypoplastic left heart 27.3 24.0 14.7 2.7 0.7     6.7
hypoplastic right heart 35.0 5.0 10.0 5.0       20.0
Conduction anomalies 16.7 22.2 28.9 20.0 5.6 1.1    
D: Respiratory 5.8 19.1 26.6 27.9 15.7 4.5 0.3 0.1
All airways 19.8 26.6 27.1 16.9 4.6 0.3 0.2  
All lung 15.9 26.7 29.7 12.9 4.3      
cystic anomalies 22.5 28.8 16.3 5.0       11.3
agenesis 29.6 25.9 20.4 1.9       11.1
hypoplasia 28.6 32.7 10.2 4.1       12.2
E: Digestive 6.4 18.8 24.7 27.5 17.4 4.1 0.4 0.8
All clefting 20.7 24.7 26.4 15.8 4.1 0.3 0.9  
lips 21.1 27.9 19.6 3.9 0.5     6.4
alveolar 21.1 21.1 21.1 15.8       10.5
isolated cleft palate 24.9 29.0 14.9 5.2 0.6 1.4   6.9
cleft palate with cleft lip 26.3 22.5 14.2 2.8   1.3   7.6
All oesophagus / stomach 23.2 19.5 28.9 19.5 4.2   1.1  
tracheo-oesophageal atresia, fistula, stenosis 18.8 28.1 19.4 5.0   1.3   4.4
All intestines 17.1 25.0 26.2 19.1 4.7 0.6 0.3  
duodenal atresia 18.3 32.3 22.6 4.3 1.1     7.5
other small bowel atresias 22.4 25.4 14.9 4.5   1.5   11.9
large bowel atresias 25.0 24.5 20.1 3.8       8.2
Hirschsprung's disease 23.8 27.5 26.3 7.5       5.0
All digestive organs 19.4 25.9 33.5 14.7 1.8      
bilary atresia 25.0 33.3 16.7 4.2       4.2
F: Urinary 6.3 17.8 26.5 28.7 15.4 4.4 0.2 0.8
All kidney 19.9 27.0 26.1 16.3 3.7 0.2 0.6  
agenesis 20.1 27.7 18.5 3.6   0.8   6.4
hypoplasia 33.3 28.9 20.0 2.2       6.7
cystic 27.8 24.4 17.6 3.7 0.3 0.9   4.0
other specific kidney 29.4 28.0 15.3 3.2 0.3 0.9   8.1
All renal pelvis / ureters 14.7 27.2 32.4 14.0 4.4 0.1 1.1  
pelviureteric obstruction 27.1 33.0 14.1 4.2 0.2 1.5   5.6
hydronephrosis, 10mm or over 28.7 33.0 15.2 3.0       4.8
All bladder / urethra 17.9 24.5 28.3 15.5 5.9   0.7  
epispadias 13.8 44.8 6.9 6.9       6.9
G: Genital 6.5 18.1 26.3 27.3 15.9 4.2 0.1 1.6
Female 16.4 23.7 30.5 16.4 6.2      
Male 18.3 26.6 26.9 15.9 4.1 0.1 1.7  
hypospadias 26.1 27.2 15.9 4.2 0.2 1.9   6.5
Intersex 15.4 19.2 42.3 15.4        
H: Endocrine, metabolic 7.5 19.0 24.2 27.6 17.3 4.1 0.2 0.2
All thyroid 16.5 26.3 26.3 18.0 3.0   0.8  
hypothyroidism 26.3 26.3 18.0 3.0   0.8   9.0
Phenylketonuria 28.6 57.1            
Cystic fibrosis 21.6 24.3 25.0 16.2 4.1      
Adrenal 16.1 24.2 37.1 14.5 1.6      
J: Blood, immune, lymphatic 7.5 19.9 25.3 26.6 18.3 2.1   0.4
Thalassaemia 12.0 20.0 44.0 12.0 8.0      
Sickle cell 25.0 28.6 16.1 14.3 3.6      
Immunodeficiency 50.0   50.0          
K: Skin 5.3 15.3 22.6 29.5 20.5 6.3   0.5
Cystic hygroma 12.7 21.3 27.8 24.0 9.2   0.3  
L: Limbs 5.5 17.1 25.8 29.0 17.2 4.7 0.2 0.4
All upper limb 17.4 25.3 27.7 17.1 4.6 0.2 0.8  
polydactyly 24.6 27.0 17.9 3.7   1.5   6.2
syndactyly 31.1 23.3 16.5 4.9   1.0   8.7
reduction defects 25.7 28.8 17.3 3.9   0.5   5.8
All lower limb 16.8 25.7 30.1 17.4 4.4 0.2 0.3  
polydactyly 24.2 27.3 17.0 3.6 0.6     5.5
syndactyly 24.4 30.4 15.2 5.3   1.0   3.3
reduction defects 26.4 28.0 16.1 2.7   0.8   8.0
dysplastic hip 25.2 31.4 18.6 5.3   0.2   4.1
non-postural talipes 27.0 25.8 16.9 4.4 0.2 0.2   6.3
Non limb-specific 18.9 27.0 24.1 16.0 5.5      
M: Musculoskeletal 10.4 19.2 24.8 24.4 16.0 4.4 0.3 0.5
All abdominal wall defects 25.1 21.5 15.3 11.8 4.3 0.6 0.2  
gastroschisis 19.0 5.6 3.0 0.4       35.3
exomphalos 23.2 22.8 20.2 8.8 0.9     9.2
All diaphragm 18.1 24.7 30.2 19.2 3.8      
hernia / agenesis 24.9 30.1 19.1 4.0       4.0
All short stature 11.5 20.7 36.8 21.8 2.3 1.1 1.1  
achondroplasia 20.8 29.2 33.3     4.2   4.2
All other specific musculoskeletal 17.7 26.3 26.6 17.0 4.4 0.1 0.6  
skull, face & neck 26.9 25.9 17.8 5.4 0.1 0.9   6.4
thorax & trunk 26.6 34.7 16.8 3.3   0.4   5.8
spine & pelvis 25.3 25.9 16.6 3.1 0.3 0.3   8.8
N: Neoplastic 7.4 11.8 32.4 30.9 13.2 4.4    
O: Genetic / multi-site disorders 3.8 9.8 15.3 22.4 28.3 18.8 1.1 0.4
All chromosomal 9.1 14.6 22.4 29.0 19.7 1.1 0.4  
trisomy 21 - Down's syndrome 10.6 20.1 34.6 25.5 1.6 0.6   1.9
trisomy 18 - Edwards' syndrome 12.2 18.4 32.9 24.9 1.8     3.6
trisomy 13 - Patau's syndrome 14.2 22.7 33.2 17.5 0.9     2.4
triploidy / polyploidy 24.1 33.5 20.3 9.0 0.5     4.7
Turner's syndrome 18.6 26.5 19.7 8.6       9.0
Klinefelter's syndrome 13.0 17.4 28.3 23.9 4.3     6.5
other anomalies sex chromosomes 17.1 18.1 22.9 21.0 1.0     3.8
deletions 23.8 29.0 15.5 4.4   0.2   8.8
other chromosome anomalies 16.4 21.7 26.8 19.9 1.0 0.6   2.8
Other genetic disorder 21.0 25.8 25.1 16.9 3.7 0.4 1.1  
P: Pregnancy related 7.7 17.4 26.4 24.7 18.4 4.3 0.3 0.7
R: Infectious 13.8 13.8 19.8 21.6 27.6 3.4    
viral 21.3 17.0 14.9 25.5 2.1      
bacterial 12.5 62.5 12.5 12.5        
fungal                
S: Suggestion of underlying anomaly 6.0 14.9 17.6 31.1 21.0 6.5 0.2 2.7
hydrops 18.6 30.4 22.8 8.7 0.4     5.3
Additional anomalies collected by SWCAR                
pyloric stenosis 26.3 22.7 10.5 3.4 0.2 0.2   13.0
inguinal hernia 24.1 29.1 18.4 4.3 0.2 0.6   6.0
balanced translocation 12.5 50.0 31.3          
café au lait spot 16.7 16.7 16.7 16.7       16.7
other branchial cleft malformations                
hydronephrosis >5mm <10mm 24.6 29.2 16.9 4.1 0.1 0.7   6.6
vesicoureteric reflux 22.7 32.0 14.4 10.3       5.2
congenital subluxation of hip 24.1 30.4 22.8 2.5       3.8