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When anomaly first suspected: Region

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* Download Region Anomaly Group data as Excel spreadsheet - contact SWCAR to get access to this dataset  [Help]

Figures reflect cases (babies/children) with one or more anomalies in that group or sub-group, occurring in a pregnancy where the presence of this anomaly (or these anomalies) was first suspected at that stage. They are expressed as a percentage of all cases of that anomaly group or sub-group notified to us. Cases with multiple anomalies within the same anomaly group or sub-group, are counted only once in that group or sub-group. For example, a baby with transposition of the great vessels and a VSD will be counted once in each of the ‘transposition great vessels’ and ‘VSD’ minor sub-groups, once in each of the ‘All complex cyanotic CHD’ and ‘All septal defects’ sub-groups, but only once in the ‘Circulatory’ group.

Anomaly grouping Antenatal At birth < 1
week
1 - 4
weeks
1 - 12 months > 12
months
Postnatal,
age not known
At
abortion
At
post mortem
Not known when 1st suspected
  % % % % % % % % % %
A: Neurological 58.7 2.7 0.9 0.4 1.1 0.2 3.2 0.2 2.4 30.2
All neural tube defects 92.8 2.3         0.3 0.5 0.2 4.0
anencephalus 97.7 1.1             0.4 0.8
spina bifida 89.2 3.1         0.6 0.6 1.2 5.3
encephalocele 74.7 5.3 1.3           8.0 10.7
Congenital hydrocephalus 71.0 2.4 0.8   0.3   0.5     24.9
Muscular dystrophy 50.0 16.7               33.3
Duchenne MD 40.0 20.0         20.0     20.0
B: Eye Ear Face Neck 2.8 23.4 2.1 0.6 2.3 0.1 14.9 1.0 17.6 35.1
All eye 26.4 10.8 1.0   2.0 0.2 8.6 0.2 2.0 48.9
anophthalmos / microphthalmos 6.7 31.7   1.7     8.3   8.3 43.3
congenital cataract   11.1 4.4       21.1     63.3
anomalies surrounding structures   2.5 1.3   3.8   13.8   3.8 75.0
All ear 20.5 24.0 1.4   0.7   7.5     45.9
external ear anomalies   36.2     2.1   6.4   12.8 42.6
sensorineural hearing loss   5.3 10.5 2.6 5.3 2.6 68.4     5.3
C: Circulatory 27.2 9.9 7.7 4.6 7.2 0.5 8.4   3.0 31.5
Disordered circulation 30.9 19.4 8.9 2.1 10.5 1.0 19.9     7.3
All septal defects 29.4 13.8 6.1 2.2 3.9 0.2 7.9 0.2 0.8 35.6
ASD (all types) 10.1 13.4 14.5 9.4 20.5 2.1 17.1   4.1 8.8
VSD 15.1 11.0 9.7 4.3 5.8 0.1 10.4   2.4 41.4
AVSD 56.6 5.6 4.0 2.8 1.2   6.0   2.0 21.7
All complex cyanotic CHD 46.7 16.9 8.9 3.8 5.0   3.0   0.6 15.1
transposition great vessels 42.2 17.7 10.4 4.7 3.1   4.2   5.2 12.5
tetralogy of Fallot 38.4 15.8 7.5 5.5 11.6   4.1   0.7 16.4
All heart valve anomalies 38.1 15.7 4.7 2.8 5.0 0.5 8.8   0.3 24.0
pulmonary valve anomalies 24.9 14.2 11.4 5.4 8.8 0.3 11.7   1.9 21.5
tricuspid valve anomalies 34.3 14.0 9.1 2.1 2.8   8.4   3.5 25.9
mitral valve anomalies 33.3 8.3 6.0 8.3 7.1   6.0   2.4 28.6
aortic valve anomalies 12.7 10.5 14.8 10.9 7.9 1.3 11.4   3.5 27.1
All vessel anomalies 46.2 11.7 6.0 3.6 4.6 0.2 6.3   1.5 19.8
pulmonary artery anomalies 24.1 9.6 7.6 8.4 10.4   10.4   6.0 23.3
aorta anomalies 31.2 9.7 11.5 7.2 8.6 0.2 3.8   9.7 17.9
All chamber anomalies 68.7 6.7 3.9 1.1 0.9   1.7   2.0 14.9
hypoplastic left heart 86.7 2.7 4.0 0.7     0.7     5.3
hypoplastic right heart 90.0 5.0             5.0  
Conduction anomalies 45.6 14.4 8.9 7.8 6.7   4.4     12.2
D: Respiratory 16.2 7.1 1.0 0.5 1.9 0.1 3.8 0.5 42.0 26.9
All airways 49.3 7.1 0.3 0.8 1.0   2.2 2.7 8.5 28.0
All lung 72.8 3.4 1.3   0.4   0.4 0.4 6.9 14.2
cystic anomalies 72.5 1.3             3.8 22.5
agenesis 5.6       1.9       88.9 3.7
hypoplasia 12.2 8.2 4.1       2.0   63.3 10.2
E: Digestive 25.9 16.8 6.4 1.1 1.5   4.1 0.3 13.7 30.3
All clefting 48.0 20.3 2.0 0.1 0.1   3.0 0.6 0.9 25.0
lips 54.9 21.1         0.5 1.0 4.4 18.1
alveolar 31.6 47.4         10.5   10.5  
isolated cleft palate 3.6 29.0 5.5 0.3 1.4   8.8 0.3 8.6 42.5
cleft palate with cleft lip 65.5 14.9 0.3       0.9 0.6 5.7 12.0
All oesophagus / stomach 44.7 21.1 6.8   0.5   1.6   1.1 24.2
tracheo-oesophageal atresia, fistula, stenosis 18.1 29.4 10.6   0.6   1.9   8.1 31.3
All intestines 46.5 12.2 7.1 0.8 0.6   2.7 0.2 1.8 28.3
duodenal atresia 57.0 9.7 8.6 2.2     2.2     20.4
other small bowel atresias 40.3 9.0 17.9 3.0     3.0   4.5 22.4
large bowel atresias 8.2 24.5 7.1   1.6   5.4   36.4 16.8
Hirschsprung's disease 1.3 5.0 35.0 1.3     6.3   1.3 50.0
All digestive organs 50.6 4.7 0.6 1.2 1.8   4.1 0.6 11.2 25.3
bilary atresia       4.2 8.3   12.5     75.0
F: Urinary 45.3 1.4 1.6 1.2 1.6 0.1 2.0 0.1 6.1 40.6
All kidney 64.8 2.0 0.2 0.5 0.4   1.4 0.4 1.3 29.1
agenesis 58.6 0.8 1.6 0.8 0.8   1.2   13.3 22.9
hypoplasia 26.7 2.2 2.2 6.7 2.2   8.9 2.2 28.9 20.0
cystic 68.2   2.0 2.6 0.3   2.0   4.3 20.7
other specific kidney 27.4 0.3 6.3 3.2 4.0 0.3 4.0   15.0 39.5
All renal pelvis / ureters 52.5 1.4   0.3 0.1   1.4   0.8 43.6
pelviureteric obstruction 27.9 1.0 4.6 2.5 2.9   2.9   3.3 54.9
hydronephrosis, 10mm or over 80.0 1.7 1.7 0.9 1.7   2.6     11.3
All bladder / urethra 65.5 6.9   0.3 0.7   1.7 0.3 2.4 22.1
epispadias   17.2     3.4   6.9     72.4
G: Genital 1.1 15.4 1.2 0.2 0.6 < 0.1 8.7 0.1 3.2 69.5
Female 40.1 12.4 0.6       4.5   2.3 40.1
Male 5.7 13.8 1.0   0.3 < 0.1 7.3 < 0.1 0.2 71.6
hypospadias   18.7 1.2   0.4   11.5   0.3 67.9
Intersex 23.1 34.6         3.8     38.5
H: Endocrine, metabolic 5.6 2.8 2.9 3.3 2.8 1.8 16.3   10.9 53.6
All thyroid 11.3 8.3 2.3 3.0 0.8 0.8 10.5     63.2
hypothyroidism     2.3 5.3 2.3   19.5   0.8 69.9
Phenylketonuria             42.9     57.1
Cystic fibrosis 10.8 6.1 4.1 0.7   0.7 6.1     71.6
Adrenal 69.4 9.7         4.8   3.2 12.9
J: Blood, immune, lymphatic 3.7 1.2 2.1 1.2 1.2   5.4   0.8 84.2
Thalassaemia             4.0     96.0
Sickle cell 5.4 1.8         10.7     82.1
Immunodeficiency         50.0         50.0
K: Skin 61.9 11.6 0.9 0.2 0.4 0.2 4.6 0.7 3.2 16.5
Cystic hygroma 96.8 1.3 0.3         0.5 0.8 0.3
L: Limbs 17.6 20.6 1.4 0.5 1.2 0.1 8.7 0.5 7.8 41.7
All upper limb 41.0 27.6 0.2 0.1 0.1 0.1 1.6 0.6 2.8 25.9
polydactyly 3.7 42.9 0.5       3.0 1.0 1.7 47.1
syndactyly 3.9 40.8     1.0   1.9 1.0 10.7 40.8
reduction defects 48.4 23.6 0.3   0.3 0.3 2.4 1.6 12.3 11.0
All lower limb 27.9 12.6 1.9 0.6 1.2   9.1 0.6 1.9 44.2
polydactyly 8.5 44.8 0.6       0.6 0.6 7.3 37.6
syndactyly 0.7 19.8 0.7       2.6 0.3 3.3 72.6
reduction defects 58.6 10.7   0.4     2.3 1.1 13.8 13.0
dysplastic hip   5.9 2.1 0.3 1.5   11.9   0.7 77.6
non-postural talipes 49.7 12.5 0.7 0.2     2.7 1.0 24.4 8.9
Non limb-specific 29.9 35.5     0.9 0.3 2.3 0.6 2.9 27.6
M: Musculoskeletal 43.4 7.2 1.5 0.7 1.9 0.5 4.7 0.5 16.1 23.6
All abdominal wall defects 91.3 3.1           0.6 1.2 3.9
gastroschisis 94.8 1.7           0.9 1.3 1.3
exomphalos 91.7 4.8             2.2 1.3
All diaphragm 72.0 9.9 1.6 1.6 2.7   1.1   1.1 9.9
hernia / agenesis 60.7 11.0 1.7 2.3 4.0   2.9   9.2 8.1
All short stature 52.9 6.9 2.3       2.3   1.1 34.5
achondroplasia 41.7 12.5 4.2   4.2   4.2     33.3
All other specific musculoskeletal 48.7 9.1 0.7 0.3 0.8 0.4 3.6 1.4 6.4 28.5
skull, face & neck 13.2 10.7 1.5 0.6 2.6 0.4 7.3 0.9 32.7 30.1
thorax & trunk 25.9 4.0 2.6 0.7 2.6 0.4 4.7 0.7 46.7 11.7
spine & pelvis 40.3 4.4 4.7 1.6 1.6 0.9 8.4   21.6 16.6
N: Neoplastic 48.5 17.6 2.9 1.5 7.4 1.5 7.4   2.9 10.3
O: Genetic / multi-site disorders 47.2 7.7 2.3 0.4 1.8 4.6 3.6 5.5 1.7 25.1
All chromosomal 54.8 7.2 1.3 0.2 1.0 3.4 2.4 4.9 0.6 24.1
trisomy 21 - Down's syndrome 61.2 14.8 2.7 0.3 0.5   1.9 2.8 1.0 14.9
trisomy 18 - Edwards' syndrome 77.3 3.6 2.0       1.1 4.2 1.1 10.7
trisomy 13 - Patau's syndrome 65.4 2.4           11.4 0.9 19.9
triploidy / polyploidy 37.3 1.4           12.7 4.2 44.3
Turner's syndrome 49.8 2.2 0.4   0.4 2.9 1.4 12.2 1.8 29.0
Klinefelter's syndrome 47.8   4.3 2.2 4.3 10.9 4.3 4.3 4.3 17.4
other anomalies sex chromosomes 36.2 3.8 1.9 1.0 1.9 15.2 4.8 1.0 1.0 33.3
deletions 17.9 3.7 4.7 1.0 8.6 25.6 10.3   2.0 26.3
other chromosome anomalies 20.1 1.2 1.5 0.3 2.5 9.2 3.6 11.9 1.0 48.7
Other genetic disorder 33.7 12.7 2.2 1.1 1.5 1.5 9.0   1.1 37.1
P: Pregnancy related 30.4 8.7 1.0 0.7 0.7 0.3 2.3 1.0 10.4 44.5
R: Infectious 17.2 12.9 5.2 1.7     7.8 0.9 40.5 13.8
viral 66.0 4.3 4.3       6.4   8.5 10.6
bacterial     12.5       12.5   25.0 50.0
fungal                    
S: Suggestion of underlying anomaly 60.7 7.5 1.9 1.0 1.7 0.5 3.9 0.2 8.4 14.2
hydrops 87.1 1.9           0.4 8.4 2.3
Additional anomalies collected by SWCAR                    
pyloric stenosis 0.2   0.2 1.1 1.6   14.6     82.2
inguinal hernia 0.1 0.5 0.1 0.5 1.2 0.1 7.1     90.5
balanced translocation 75.0                 25.0
café au lait spot   16.7 16.7             66.7
other branchial cleft malformations                    
hydronephrosis >5mm <10mm 37.1 0.1 1.7 1.1 0.2   1.5   1.4 56.8
vesicoureteric reflux 19.6 1.0 10.3 10.3 30.9   15.5     12.4
congenital subluxation of hip   2.5   2.5 5.1   6.3     83.5